Joint Degradation in a Monkey Model of Collagen-Induced Arthritis: Role of Cathepsin K Based on Biochemical Markers and Histological Evaluation

Figure 2

Association between joint swelling score and increases in urinary CTX-II/Cr, CTX-I/Cr, NTX/Cr, and DPD/Cr at each time point. (Spearman rank correlation). CTX-I, C-telopeptide fragment of type I collagen; CTX-II, C-telopeptide fragment of type II collagen; DPD, deoxypyridinoline; NTX, N-telopeptide fragment of type I collagen; Cr, creatinine.