Research Article

Medication Adherence and Coping Strategies in Patients with Rheumatoid Arthritis: A Cross-Sectional Study

Table 1

Participant characteristics and medication adherence.

N (% of total) 
N=120 (100%)
Medication adherent 
(% within variable)  
N=63 (52.5%)
Not completely medication adherent 
(% within variable)  
N=57 (47.5%)
p-values

Sex
 Female99 (82.5)57 (57.6) 42 (42.4) 0.016
 Male21 (17.5)6 (28.6) 15 (71.4)
Age
 < 45 years29 (24.2)8 (27.6) 21(72.4) 0.008
 45 – 65 years65 (54.2)39 (60.0)26 (40.0)
 > 65 years26 (21.7)16 (61.5)10 (38.5)
Marital status
 Single16(13.3)5 (31.3)11 (68.8)0.101
 Married69 (57.5)35 (50.7)34 (49.3)
 Divorced/living separated24 (20.0)17 (70.8)7 (29.7)
 Widowed11 (9.2)6 (54.5)5 (45.5)
Educational level
 Compulsory/lower secondary31 (25.8)16 (51.6)15 (48.4)0.785
 Secondary school/apprenticeship68 (56.7)34 (50.0)34 (50.0)
 Higher education9 (7.5)6 (66.7)3 (33.3)
 Other12 (10.0)7 (58.3)5 (41.7)
Monthly net income
 < 1000€ (1120$)23 (19.2)14 (60.9)9 (39.1)0.168
 1001–2000€ (1121 -2240$)68 (56.7)38 (55.9)30 (44.1)
 2001–3000€ (2241-3360$)20 (16.7)6 (30.0)14 (70.0)
 > 3000€ (>3361$)9 (7.5)5 (55.6)4 (44.4)
Disease duration
 >10years35 (29.2)12 (34.4) 23 (65.7) 0.048
 5-10 years40 (33.3)25 (62.5)15 (37.5)
 1-4 years37 (30.8)20 (54.1)17 (45.9)
 <1year8 (6.7)6 (75.0)2 (25.0)
RA treatment
 sDMARDs77 (64.2)42 (54.5)35 (45.5)0.246
 bDMARDs8 (6.7)2 (25)6 (75)
 DMRAD + Biologic30 (25)15 (50)15 (50)
 Corticosteroids5 (4.2)4 (80)1 (20)
Number of other medications
 No other medications34 (28.3)16 (47.1)18 (52.9)0.120
 1–2 other medications45 (37.5)28 (62.2)17 (29.8)
 3-4 other medications19 (37.5)6 (31.6)13 (68.4)
 >4 other medications22 (18.3)13 (59.1)9 (40.9)

Descriptive statistic of demographic and clinical variable distribution, medication adherence, and their association with demographic and clinical variables. Values are absolute numbers (and percent of total or percent within variable).
means significantly different from expected value in post hoc testing.
sDMARDs: synthetic disease-modifying anti-rheumatic drugs; bDMARDs: biologic disease-modifying anti-rheumatic drugs.