Research Article

Role of Secreted Frizzled-Related Protein 1 and Tumor Necrosis Factor-α (TNF-α) in Bone Loss of Patients with Rheumatoid Arthritis

Table 1

Characteristics of subjects.

CharacteristicsResult

Age (year),
Duration of disease (year), median (min score–max score)5 (1-19)
BMI, median (min score–max score)21.82 (14.5–37)
Glucocorticoid dosage, (%)
(i) None7 (18.4%)
(ii)  mg25 (65.8%)
(iii) Methylprednisolone 4 mg6 (15.8%)
RA treatment, (%)
(i) Monotherapy MTX21 (55.3%)
(ii) Combination of 2 DMARD9 (23.7%)
(iii) Combination of 3 DMARD1 (2.6%)
(iv) Monotherapy DMARD other than MTX7 (18.4%)
CRP (mg/dL), median (min score–max score)4.2 (0.6–88.4)
DAS28 CRP, (%)
(i) Remission17 (44.8%)
(ii) Low6 (15.8%)
(iii) Moderate14 (36.8%)
(iv) High1 (2.6%)
TNF-α (pg/mL), median (min score–max score)10.58 (7–17.7)
SFRP-1 (ng/mL),
CTX (ng/mL),
P1NP (pg/mL), median (min score–max score)34.04 (2.46–220.61)