International Journal of Rheumatology / 2020 / Article / Fig 2

Research Article

Are Stem Cells Derived from Synovium and Fat Pad Able to Treat Induced Knee Osteoarthritis in Rats?

Figure 2

A typical histological section from all groups’ surface of articular cartilage (H&E, ×200). E2 group: synovial membrane-based stem cells, arranged chondrocyte in columnar cluster along with continuous and smooth surface of articular hyaline cartilage with no foci of abnormal calcification; E1 group: adipose tissue-derived stem cells, the surface of articular cartilage was mainly continues composed of fibrocartilage tissue arranged in clusters, and the subchondral bone was detached with increased remodeling; C2 group: treated with Hyalgan, the surface of articular cartilage was continuous mainly composed of fibrocartilage with foci of hyaline cartilage cluster; and C1 nontreated group, the surface of articular cartilage was completely destructive and composed of disorganized fibrocartilage and fibrous tissues, and the subchondral bone was detached.

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