Table 1: Data comparison of minimal stimulation and high-dose stimulation protocols for low responders. Not significant results are denoted by NS.

Minimum stimulationHigh stimulation value

Number of patients7071
Age (yr)39.4 ± 3.239.2 ± 4.0NS
Peak estradiol (pmol/L)1580.8 ± 1141.25279.4 ± 3295.1 < 0.001
Gonadotropin total dose (IU)1332.9 ± 435.75575.2 ± 1945.0 < 0.001
Antral follicle count3.7 ± 1.04.5 ± 0.7 < 0.001
Number of oocytes retrieved 2.9 ± 1.53.5 ± 1.5NS
Number of fertilized oocytes1.5 ± 1.11.5 ± 1.2NS
Cancellation rate3/71 (4.2%)4/79 (5.0%)NS
Number of embryos transferred1.8 ± 0.71.4 ± 1.2NS
Clinical pregnancy rate/cycle22/70 (31.4%)9/71 (12.7%) < 0.05
Live birth rate15/70 (21.4%)5/71 (7.0%) < 0.05