Clinical Study
Comparison of IVF Outcomes between Minimal Stimulation and High-Dose Stimulation for Patients with Poor Ovarian Reserve
Table 1
Data comparison of minimal stimulation and high-dose stimulation protocols for low responders. Not significant results are denoted by NS.
| | Minimum stimulation | High stimulation | value |
| Number of patients | 70 | 71 | | Age (yr) | 39.4 ± 3.2 | 39.2 ± 4.0 | NS | Peak estradiol (pmol/L) | 1580.8 ± 1141.2 | 5279.4 ± 3295.1 | < 0.001 | Gonadotropin total dose (IU) | 1332.9 ± 435.7 | 5575.2 ± 1945.0 | < 0.001 | Antral follicle count | 3.7 ± 1.0 | 4.5 ± 0.7 | < 0.001 | Number of oocytes retrieved | 2.9 ± 1.5 | 3.5 ± 1.5 | NS | Number of fertilized oocytes | 1.5 ± 1.1 | 1.5 ± 1.2 | NS | Cancellation rate | 3/71 (4.2%) | 4/79 (5.0%) | NS | Number of embryos transferred | 1.8 ± 0.7 | 1.4 ± 1.2 | NS | Clinical pregnancy rate/cycle | 22/70 (31.4%) | 9/71 (12.7%) | < 0.05 | Live birth rate | 15/70 (21.4%) | 5/71 (7.0%) | < 0.05 |
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