Normal Pregnancy Is Associated with Changes in Central Hemodynamics and Enhanced Recruitable, but Not Resting, Endothelial Function
Table 2
Central (aortic) and peripheral arterial structural and functional parameters.
Variable
NP
HP
value
Heart rate (beats/minute)
73.8 ± 10.8
85.0 ± 10.0
0.007
Peripheral SBP (mmHg)
113.0 ± 11.2
112.0 ± 9.2
0.740
Peripheral DBP (mmHg)
72.4 ± 8.2
62.5 ± 8.9
0.004
MBP (mmHg)
89.0 ± 8.5
78.6 ± 5.7
0.002
Peripheral PP (mmHg)
45.9 ± 9.3
49.8 ± 17.8
0.235
Central SBP (mmHg)
104.2 ± 9.9
95.8 ± 6.8
0.043
Central DBP (mmHg)
72.2 ± 8.2
63.4 ± 9.4
0.016
Central PP (mmHg)
32.0 ± 4.3
32.4 ± 11.0
0.683
Amplification ratio (pPP/cPP)
1.31 ± 0.21
1.51 ± 0.16
0.006
AIx@75 (%)
18.8 ± 10.1
8.9 ± 8.6
0.019
Carotid-to-radial PWV (m/s)
8.4 ± 1.1
6.8 ± 1.4
0.003
Brachial SD (mm)
3.1 ± 0.3
3.9 ± 0.3
<0.001
Brachial DD (mm)
2.9 ± 0.3
3.7 ± 0.3
<0.001
Carotid-to-femoral PWV (m/s)
8.1 ± 1.3
6.8 ± 0.9
0.022
Right CCA SD (mm)
6.8 ± 0.6
7.0 ± 0.5
0.311
Right CCA DD (mm)
6.7 ± 0.5
6.9 ± 0.7
0.388
Right CCA (mmHg)
416.9 ± 157.6
350.6 ± 110.0
0.301
Right CIMT (mm)
0.550 ± 0.077
0.462 ± 0.089
0.044
Left CCA SD (mm)
6.6 ± 0.6
7.2 ± 0.4
0.040
Left CCA DD (mm)
6.0 ± 0.5
6.5 ± 0.3
0.062
Left CCA (mmHg)
401.8 ± 155.7
352.7 ± 179.0
0.702
Left CIMT (mm)
0.572 ± 0.090
0.519 ± 0.080
0.146
Values are expressed as means ± SD. indicates . All comparisons were determined using two-tailed unpaired Student -test. NP: nonpregnant women; HP: healthy pregnant women; SBP, DBP, MBP, and PP: systolic, diastolic, mean, and pulse pressure, respectively. pPP and cPP: peripheral and central pulse pressure, respectively. AIx@75: augmentation index adjusted to a heart rate of 75 beats/minute; PWV: pulse wave velocity; SD and DD: systolic and diastolic diameter, respectively; : Peterson’s or pressure-strain elastic modulus; CCA: common carotid artery; CIMT: carotid intima-media thickness.
