Research Article

Combined Intranasal Insulin/Saxagliptin/Metformin Therapies Ameliorate the Effect of Combined Oral Contraceptive- (COC-) Induced Metabolic Syndrome (MetS) with a Major Target on Glucose Metabolism in Adult Female Wistar Rats

Figure 7

(a–c) No statistically significant alterations across the test groups for the inflammatory mediators: TNF-α, IL-6, and IL-1β, respectively. However, there is a nonstatistical increase in the level of TNF-α and IL-6 in the COC group and a subsequent reduction in the MET and INI+MET groups for both mediators, ; , .
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