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International Journal of Spectroscopy
Volume 2012 (2012), Article ID 350684, 7 pages
Review Article

The Nanofabrication and Application of Substrates for Surface-Enhanced Raman Scattering

1Advanced Materials Laboratory, Department of Materials Science and Engineering, Tsinghua University, Beijing 100084, China
2Institute of Nuclear and New Energy Technology, Tsinghua University, Beijing 100084, China

Received 8 September 2012; Revised 29 November 2012; Accepted 29 November 2012

Academic Editor: Rolf W. Berg

Copyright © 2012 Xian Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Surface-enhanced Raman scattering (SERS) was discovered in 1974 and impacted Raman spectroscopy and surface science. Although SERS has not been developed to be an applicable detection tool so far, nanotechnology has promoted its development in recent decades. The traditional SERS substrates, such as silver electrode, metal island film, and silver colloid, cannot be applied because of their enhancement factor or stability, but newly developed substrates, such as electrochemical deposition surface, Ag porous film, and surface-confined colloids, have better sensitivity and stability. Surface enhanced Raman scattering is applied in other fields such as detection of chemical pollutant, biomolecules, DNA, bacteria, and so forth. In this paper, the development of nanofabrication and application of surface-enhanced Ramans scattering substrate are discussed.