Research Article

Development and Validation of a Discriminating In Vitro Dissolution Method for Oral Formulations Containing Satranidazole

Table 8

Change in wavelength.

Time (minutes)At 318At 320At 322

Average % release ± SD
000   
58.95 ± 0.545685.12 ± 0.767883.98 ± 0.6789
1034.01 ± 0.434598.23 ± 0.667897.31 ± 0.8012
1544.25 ± 0.598799.81 ± 0.897898.12 ± 0.5612
3066.87 ± 0.6745101.29 ± 0.7809 99.24 ± 0.6769
4577.12 ± 0.756876.84 ± 0.598277.46 ± 0.8145
6085.93 ± 0.476887.09 ± 0.378085.76 ± 0.4568

Average at 60 min86.26 ± 0.6744
% RSD at 60 min0.839