Table of Contents Author Guidelines Submit a Manuscript
International Journal of Surgical Oncology
Volume 2010 (2010), Article ID 214919, 8 pages
http://dx.doi.org/10.1155/2010/214919
Clinical Study

Outcome in Advanced Ovarian Cancer following an Appropriate and Comprehensive Effort at Upfront Cytoreduction: A Twenty-Year Experience in a Single Cancer Institute

1Department of Surgery, Institut Curie, 25 rue d’Ulm, 75005 Paris, France
2Department of Medical Oncology, Institut Curie, 25 rue d’Ulm, 75005 Paris, France
3Department of Biostatistics, Institut Curie, 25 rue d’Ulm, 75005 Paris, France
4Department of Pathology, Institut Curie, 25 rue d’Ulm, 75005 Paris, France
5Department of Translational Research, Institut Curie, 25 rue d’Ulm, 75005 Paris, France
6Department of Radiotherapy, Institut Curie, 25 rue d’Ulm, 75005 Paris, France
7Department of Radiology, Institut Curie, 25 rue d’Ulm, 75005 Paris, France

Received 1 September 2009; Revised 6 May 2010; Accepted 11 June 2010

Academic Editor: Sanjeev Misra

Copyright © 2010 Anne Marszalek et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. B. Trétarre, L. Remontet, F. Ménégoz et al., “Ovarian cancer: incidence and mortality in France,” Journal de Gynecologie Obstetrique et Biologie de la Reproduction, vol. 34, no. 2, pp. 154–161, 2005. View at Google Scholar · View at Scopus
  2. A. P. M. Heintz, F. Odicino, P. Maisonneuve et al., “Carcinoma of the ovary,” Journal of Epidemiology and Biostatistics, vol. 6, no. 1, pp. 107–138, 2001. View at Google Scholar · View at Scopus
  3. R. E. Bristow, R. S. Tomacruz, D. K. Armstrong, E. L. Trimble, and F. J. Montz, “Survival effect of maximal cytoreductive surgery for advanced epithelial ovarian cancer during the platinum era: a meta-analysis,” Journal of Clinical Oncology, vol. 20, pp. 1248–1259, 2002. View at Google Scholar
  4. P. Venesmaa and O. Ylikorkala, “Morbidity and mortality associated with primary and repeat operations for ovarian cancer,” Obstetrics and Gynecology, vol. 79, no. 2, pp. 168–172, 1992. View at Google Scholar · View at Scopus
  5. Y. Shimizu, S. Kamoi, S. Amada, F. Akiyama, and S. G. Silverberg, “Toward the development of a universal grading system for ovarian epithelial carcinoma: testing of a proposed system in a series of 461 patients with uniform treatment and follow-up,” Cancer, vol. 82, no. 5, pp. 893–901, 1998. View at Publisher · View at Google Scholar · View at Scopus
  6. A. Malpica, M. T. Deavers, K. Lu et al., “Grading ovarian serous carcinoma using a two-tier system,” American Journal of Surgical Pathology, vol. 28, no. 4, pp. 496–504, 2004. View at Publisher · View at Google Scholar · View at Scopus
  7. D. S. Chi, C. C. Franklin, D. A. Levine et al., “Improved optimal cytoreduction rates for stages IIIC and IV epithelial ovarian, fallopian tube, and primary peritoneal cancer: a change in surgical approach,” Gynecologic Oncology, vol. 94, no. 3, pp. 650–654, 2004. View at Publisher · View at Google Scholar · View at Scopus
  8. A. Obermair, S. Hagenauer, D. Tamandl et al., “Safety and efficacy of low anterior en bloc resection as part of cytoreductive surgery for patients with ovarian cancer,” Gynecologic Oncology, vol. 83, no. 1, pp. 115–120, 2001. View at Publisher · View at Google Scholar · View at Scopus
  9. R. E. Bristow, M. G. Del Carmen, H. S. Kaufman, and F. J. Montz, “Radical oophorectomy with primary stapled colorectal anastomosis for resection of locally advanced epithelial ovarian cancer,” Journal of the American College of Surgeons, vol. 197, no. 4, pp. 565–574, 2003. View at Publisher · View at Google Scholar · View at Scopus
  10. L.-M. Chen, R. S. Leuchter, L. D. Lagasse, and B. Y. Karlan, “Splenectomy and surgical cytoreduction for ovarian cancer,” Gynecologic Oncology, vol. 77, no. 3, pp. 362–368, 2000. View at Publisher · View at Google Scholar · View at Scopus
  11. Y. Yildirim and M. Sanci, “The feasibility and morbidity of distal pancreatectomy in extensive cytoreductive surgery for advanced epithelial ovarian cancer,” Archives of Gynecology and Obstetrics, vol. 272, no. 1, pp. 31–34, 2005. View at Publisher · View at Google Scholar · View at Scopus
  12. D. F. Silver, “Full-thickness diaphragmatic resection with simple and secure closure to accomplish complete cytoreductive surgery for patients with ovarian cancer,” Gynecologic Oncology, vol. 95, no. 2, pp. 384–387, 2004. View at Publisher · View at Google Scholar · View at Scopus
  13. S. M. Eisenkop, R. L. Friedman, and H.-J. Wang, “Complete cytoreductive surgery is feasible and maximizes survival in patients with advanced epithelial ovarian cancer: a prospective study,” Gynecologic Oncology, vol. 69, no. 2, pp. 103–108, 1998. View at Publisher · View at Google Scholar · View at Scopus
  14. C. Scarabelli, A. Gallo, S. Franceschi et al., “Primary cytoreductive surgery with rectosigmoid colon resection for patients with advanced epithelial ovarian carcinoma,” Cancer, vol. 88, no. 2, pp. 389–397, 2000. View at Publisher · View at Google Scholar · View at Scopus
  15. D. S. Chi, J. B. Liao, L. F. Leon et al., “Identification of prognostic factors in advanced epithelial ovarian carcinoma,” Gynecologic Oncology, vol. 82, no. 3, pp. 532–537, 2001. View at Publisher · View at Google Scholar · View at Scopus
  16. S. M. Eisenkop, N. M. Spirtos, R. L. Friedman, W.-C. M. Lin, A. L. Pisani, and S. Perticucci, “Relative influences of tumor volume before surgery and the cytoreductive outcome on survival for patients with advanced ovarian cancer: a prospective study,” Gynecologic Oncology, vol. 90, no. 2, pp. 390–396, 2003. View at Publisher · View at Google Scholar · View at Scopus
  17. E. L. Eisenhauer, N. R. Abu-Rustum, Y. Sonoda et al., “The addition of extensive upper abdominal surgery to achieve optimal cytoreduction improves survival in patients with stages IIIC-IV epithelial ovarian cancer,” Gynecologic Oncology, vol. 103, no. 3, pp. 1083–1090, 2006. View at Publisher · View at Google Scholar · View at Scopus
  18. F. Di Re, R. Fontanelli, F. Raspagliesi, and E. Di Re, “Pelvic and para-aortic lymphadenectomy in cancer of the ovary,” Bailliere's Clinical Obstetrics and Gynaecology, vol. 3, no. 1, pp. 131–142, 1989. View at Google Scholar · View at Scopus
  19. E. Burghardt, M. Lahousen, and H. Stettner, “The significance of pelvic and para-aortic lymphadenectomy in the operative treatment of ovarian cancer,” Bailliere's Clinical Obstetrics and Gynaecology, vol. 3, no. 1, pp. 157–165, 1989. View at Google Scholar · View at Scopus
  20. T. Onda, H. Yoshikawa, H. Yokota, T. Yasugi, and Y. Taketani, “Assessment of metastases to aortic and pelvic lymph nodes in epithelial ovarian carcinoma: a proposal for essential sites for lymph node biopsy,” Cancer, vol. 78, no. 4, pp. 803–808, 1996. View at Publisher · View at Google Scholar · View at Scopus
  21. P. Morice, F. Joulie, S. Camatte et al., “Lymph node involvement in epithelial ovarian cancer: analysis of 276 pelvic and paraaortic lymphadenectomies and surgical implications,” Journal of the American College of Surgeons, vol. 197, no. 2, pp. 198–205, 2003. View at Publisher · View at Google Scholar · View at Scopus
  22. J. B. Trimbos, I. Vergote, G. Bolis et al., “Impact of adjuvant chemotherapy and surgical staging in early-stage ovarian carcinoma: European Organisation for Research and Treatment of Cancer-Adjuvant ChemoTherapy in Ovarian Neoplasm trial,” Journal of the National Cancer Institute, vol. 95, no. 2, pp. 113–125, 2003. View at Google Scholar · View at Scopus
  23. P.-C. Wu, J.-Y. Qu, and J.-H. Lang, “Lymph node metastasis of ovarian cancer: a preliminary survey of 74 cases of lymphadenectomy,” American Journal of Obstetrics and Gynecology, vol. 155, no. 5, pp. 1103–1108, 1986. View at Google Scholar · View at Scopus
  24. E. Burghardt, F. Girardi, M. Lahousen, K. Tamussino, and H. Stettner, “Patterns of pelvic and paraaortic lymph node involvement in ovarian cancer,” Gynecologic Oncology, vol. 40, no. 2, pp. 103–106, 1991. View at Publisher · View at Google Scholar · View at Scopus
  25. F. Di Re, G. Baiocchi, R. Fontanelli et al., “Systematic pelvic and paraaortic lymphadenectomy for advanced ovarian cancer: prognostic significance of node metastases,” Gynecologic Oncology, vol. 62, no. 3, pp. 360–365, 1996. View at Publisher · View at Google Scholar · View at Scopus
  26. P. B. Panici, A. Maggioni, N. Hacker et al., “Systematic aortic and pelvic lymphadenectomy versus resection of bulky nodes only in optimally debulked advanced ovarian cancer: a randomized clinical trial,” Journal of the National Cancer Institute, vol. 97, no. 8, pp. 560–566, 2005. View at Publisher · View at Google Scholar · View at Scopus
  27. W. A. Cliby, G. D. Aletti, T. O. Wilson, and K. C. Podratz, “Is it justified to classify patients to stage IIIC epithelial ovarian cancer based on nodal involvement only?” Gynecologic Oncology, vol. 103, no. 3, pp. 797–801, 2006. View at Publisher · View at Google Scholar · View at Scopus
  28. W. P. Mcguire, W. J. Hoskins, M. F. Brady et al., “Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer,” New England Journal of Medicine, vol. 334, no. 1, pp. 1–6, 1996. View at Publisher · View at Google Scholar · View at Scopus
  29. M. J. Piccart, K. Bertelsen, G. Stuart et al., “Long-term follow-up confirms a survival advantage of the paclitaxel-cisplatin regimen over the cyclophosphamide-cisplatin combination in advanced ovarian cancer,” International Journal of Gynecological Cancer, vol. 13, supplement 2, pp. 144–148, 2003. View at Publisher · View at Google Scholar · View at Scopus
  30. D. S. P. Tan, C. Rothermundt, K. Thomas et al., ““BRCAness” syndrome in ovarian cancer: a case-control study describing the clinical features and outcome of patients with epithelial ovarian cancer associated with BRCA1 and BRCA2 mutations,” Journal of Clinical Oncology, vol. 26, no. 34, pp. 5530–5536, 2008. View at Publisher · View at Google Scholar · View at Scopus
  31. W. E. Winter III, G. L. Maxwell, C. Tian et al., “Prognostic factors for stage III epithelial ovarian cancer: a Gynecologic Oncology Group study,” Journal of Clinical Oncology, vol. 25, no. 24, pp. 3621–3627, 2007. View at Publisher · View at Google Scholar · View at Scopus
  32. D. Daya, L. Nazerali, and G. L. Frank, “Metastatic ovarian carcinoma of large intestinal origin simulating primary ovarian carcinoma: a clinicopathologic study of 25 cases,” American Journal of Clinical Pathology, vol. 97, no. 6, pp. 751–758, 1992. View at Google Scholar · View at Scopus
  33. D. J. Gersell, “Metastatic ovarian tumors: still a challenge,” American Journal of Clinical Pathology, vol. 97, no. 6, pp. 745–747, 1992. View at Google Scholar · View at Scopus
  34. A. Berchuck, E. S. Iversen, J. M. Lancaster et al., “Prediction of optimal versus suboptimal cytoreduction of advanced-stage serous ovarian cancer with the use of microarrays,” American Journal of Obstetrics and Gynecology, vol. 190, no. 4, pp. 910–925, 2004. View at Publisher · View at Google Scholar · View at Scopus