International Journal of Surgical Oncology / 2011 / Article / Tab 4

Review Article

Lymph Node Dissection in Curative Gastrectomy for Advanced Gastric Cancer

Table 4

Randomized controlled trials comparing D1 with D2/D3.

StudyCountryComparisonPostoperative
morbidity
Postoperative
mortality
5-year survival

Dutch trial
(1989–1993)
NetherlandsD1
D2
25%
43%
4%
10%
45%
47%
HR 1.00
(95% CI, 0.82–1.22)
MRC trial
(1987–1994)
UKD1
D2
28%
46%
6.5%
13%
35%
33%
HR 1.10
(95% CI, 0.87–1.39)
Taiwanese trial
(1993–1999)
TaiwanD1
D3
7.3%
17.1%
0%
0%
53.6%
59.5%
HR 0.49
(95% CI, 0.32–0.77)
IGCSG trial
(1999–2002)
ItalyD1
D2
10.5%
16.3%
0%
1.3%
(N.S)
Under analysis

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