International Journal of Surgical Oncology / 2012 / Article / Tab 2

Clinical Study

Metastatic Medulloblastoma in Childhood: Chang's Classification Revisited

Table 2

Univariate and multivariate analysis of early Complete Response (CR) to sandwich chemotherapy.

Univariate analysisMultivariate analysis
CR (%)HRIC (95%) valueHRIC (95%) value

Chang’staging
 M1 ( )11 (50%)10.00610.002
 M2 ( )3 (12%)7.31.7–31.89.82.0–46.9
 M3 ( )13 (19%)4.41.6–12.36.72.1–21.6

Qualitative classification
 Positive CSF ( )11 (50%)10.00510.002
 Nodular ( )8 (22%)3.51.1–11.06.31.7–23.7
 Laminar ( )8 (14%)6.42.1–19.58.12.4–27.2

Quantitative classification
 Positive CSF ( )11 (50%)10.00310.001
 Localized ( )7 (27%)2.70.8–9.04.21.1–15.8
 Extensive ( )9 (13%)6.72.2–19.89.72.9–32.9

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