International Journal of Surgical Oncology / 2012 / Article / Tab 3

Clinical Study

Metastatic Medulloblastoma in Childhood: Chang's Classification Revisited

Table 3

Univariate and multivariate analysis of Overall Survival (OS).

Univariate analysisMultivariate analysis
5-year OSHRIC (95%) valueHRIC (95%) value

Chang’s classification
 M1 ( )47%10.9510.73
 M2 ( )51%0.90.4–1.90.90.4–2.0
 M3 ( )42%1.00.5–1.91.20.6–2.2

Qualitative classification
 Positive CSF (n = 22)47%10.0410.17
 Nodular ( )59%0.60.3–1.20.70.3–1.6
 Laminar ( )35%1.30.7–2.51.30.7–2.4

Quantitative classification
 Positive CSF ( )47%10.1210.16
 Localized ( )65%0.60.3–1.30.70.3–1.5
 Extensive ( )36%1.20.6–2.21.30.7–2.4

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