International Journal of Surgical Oncology / 2012 / Article / Tab 2

Review Article

Atypical Ductal Hyperplasia at the Margin of Lumpectomy Performed for Early Stage Breast Cancer: Is there Enough Evidence to Formulate Guidelines?

Table 2

Atypical ductal hyperplasia (ADH) and ipsilateral breast tumor recurrence (IBTR).

Investigatorno. BCS specimensno. lumpectomy + for ADHIBTR ADH (+) no. (%)IBTR in ADH (−) no. (%)Median Followup (years)

Goldstein et al. [33]94543/54 (5.6)0/36 (0)′′6.5
Fowble et al. [34]460991/99 (1.0)17/329 (5.2)4.8
Greene et al. [35]155*870/87 (0%)**1/68 (1.5)**2.2

′ADH (+) at margin more recurrence than ADH (−) at margin .
′′Represents lesions negative for both ADH and COL.
ADH involved somewhere in specimen, not specifically involving margin.
*Lumpectomy performed for ADH, no malignancy in original specimen.
**denotes malignancy development and not recurrence as initial lumpectomy was negative for malignancy.

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