Table of Contents Author Guidelines Submit a Manuscript
International Journal of Surgical Oncology
Volume 2012, Article ID 301530, 7 pages
http://dx.doi.org/10.1155/2012/301530
Clinical Study

The Significance of Splenectomy for Advanced Proximal Gastric Cancer

Department of Surgery, Niigata Cancer Center Hospital, Niigata 951-8566, Japan

Received 13 January 2012; Accepted 11 March 2012

Academic Editor: Marco Bernini

Copyright © 2012 Atsushi Nashimoto et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. T. Toge, A. Kameda, K. Kuroi, Y. Seto, H. Yamada, and T. Hattori, “The role of the spleen in immunosuppression and the effects of splenectomy on prognosis in gastric cancer patients,” Nippon Geka Gakkai zasshi, vol. 86, no. 9, pp. 1120–1123, 1985. View at Google Scholar · View at Scopus
  2. K. Okajima and H. Isozaki, “Splenectomy for treatment of gastric cancer: Japanese experience,” World Journal of Surgery, vol. 19, no. 4, pp. 537–540, 1995. View at Publisher · View at Google Scholar · View at Scopus
  3. S. Ishikawa, S. Shimada, N. Miyanari, M. Hirota, H. Takamori, and H. Baba, “Pattern of lymph node involvement in proximal gastric cancer,” World Journal of Surgery, vol. 33, no. 8, pp. 1687–1692, 2009. View at Publisher · View at Google Scholar · View at Scopus
  4. T. Sano and T. Aiko, “Japanese gastric cancer treatment guidelines 2010 (ver. 3),” Gastric Cancer, vol. 14, no. 2, pp. 113–123, 2011. View at Publisher · View at Google Scholar · View at Scopus
  5. J. J. Bonenkamp, J. Hermans, M. Sasako, and C. J. H. Van De Velde, “Extended lymph-node dissection for gastric cancer,” New England Journal of Medicine, vol. 340, no. 12, pp. 908–914, 1999. View at Publisher · View at Google Scholar · View at Scopus
  6. A. Cuschieri, P. Fayers, J. Fielding et al., “Postoperative morbidity and mortality after D1 and D2 resections for gastric cancer: preliminary results of the MRC randomised controlled surgical trial,” Lancet, vol. 347, no. 9007, pp. 995–999, 1996. View at Publisher · View at Google Scholar · View at Scopus
  7. S. S. Brar, R. Seevaratnam, R. Cardoso et al., “A systematic review of spleen and pancreas preservation in extended lymphadenectomy for gastric cancer,” Gastric Cancer. In press.
  8. Japanese Gastric Cancer Association, “Japanese classification of gastric carcinoma: 2nd English edition,” Gastric Cancer, vol. 1, pp. 10–24, 1998. View at Google Scholar
  9. M. Sasako, P. McCullouch, T. Kinoshita, and K. Maruyama, “New method to evaluate the therapeutic value of lymph node dissection for gastric cancer,” British Journal of Surgery, vol. 82, no. 3, pp. 346–351, 1995. View at Publisher · View at Google Scholar · View at Scopus
  10. M. S. Brady, A. Rogatko, L. L. Dent, and M. H. Shiu, “Effect of splenectomy on morbidity and survival following curative gastrectomy for carcinoma,” Archives of Surgery, vol. 126, no. 3, pp. 359–364, 1991. View at Google Scholar · View at Scopus
  11. J. P. Griffith, H. M. Sue-Ling, I. Martin et al., “Preservation of the spleen improves survival after radical surgery for gastric cancer,” Gut, vol. 36, no. 5, pp. 684–690, 1995. View at Google Scholar · View at Scopus
  12. S. J. Kwon, J. I. Lee, D. W. Choi et al., “Prognostic impact of splenectomy on gastric cancer: results of the Korean Gastric Cancer Study Group,” World Journal of Surgery, vol. 21, no. 8, pp. 837–844, 1997. View at Publisher · View at Google Scholar · View at Scopus
  13. H. J. Wanebo, B. J. Kennedy, D. P. Winchester, A. K. Stewart, and A. M. Fremgen, “Role of splenectomy in gastric cancer surgery: adverse effect of elective splenectomy on longterm survival,” Journal of the American College of Surgeons, vol. 185, no. 2, pp. 177–184, 1997. View at Publisher · View at Google Scholar · View at Scopus
  14. Y. Maehara, S. Moriguchi, M. Yoshida, I. Takahashi, D. Korenaga, and K. Sugimachi, “Splenectomy does not correlate with length of survival in patients undergoing curative total gastrectomy for gastric carcinoma: univariate and multivariate analyses,” Cancer, vol. 67, no. 12, pp. 3006–3009, 1991. View at Google Scholar · View at Scopus
  15. E. Otsuji, T. Yamaguchi, K. Sawai, K. Okamoto, and T. Takahashi, “Total gastrectomy with simultaneous pancreaticosplenectomy or splenectomy in patients with advanced gastric carcinoma,” British Journal of Cancer, vol. 79, no. 11-12, pp. 1789–1793, 1999. View at Google Scholar · View at Scopus
  16. Y. Tanizawa and M. Terashima, “Lymph node dissection in the resection of gastric cancer: review of existing evidence,” Gastric Cancer, vol. 13, no. 3, pp. 137–148, 2010. View at Publisher · View at Google Scholar · View at Scopus
  17. W. Yu, G. S. Choi, and H. Y. Chung, “Randomized clinical trial of splenectomy versus splenic preservation in patients with proximal gastric cancer,” British Journal of Surgery, vol. 93, no. 5, pp. 559–563, 2006. View at Publisher · View at Google Scholar · View at Scopus
  18. T. Kosuga, D. Ichikawa, K. Okamoto et al., “Survival benefits from splenic hilar lymph node dissection by splenectomy in gastric cancer patients: relative comparison of the benefits in subgroups of patients,” Gastric Cancer, vol. 14, no. 2, pp. 172–177, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. K. Aoyagi, K. Kouhuji, M. Miyagi et al., “Prognosis of metastatic splenic hilum lymph node in patients with gastric cancer after total gastrectomy and splenectomy,” World Journal of Hepatology, vol. 27, no. 2, pp. 81–86, 2010. View at Google Scholar
  20. K. Maruyama, K. Okabayashi, and T. Kinoshita, “Progress in gastric cancer surgery in Japan and its limits of radicality,” World Journal of Surgery, vol. 11, no. 4, pp. 418–425, 1987. View at Google Scholar · View at Scopus
  21. C. H. Zhang, W. H. Zhan, Y. L. He, C. Q. Chen, M. J. Huang, and S. R. Cai, “Spleen preservation in radical surgery for gastric cardia cancer,” Annals of Surgical Oncology, vol. 14, no. 4, pp. 1312–1319, 2007. View at Publisher · View at Google Scholar · View at Scopus
  22. S. H. Shin, H. Jung, S. H. Choi et al., “Clinical significance of splenic Hilar lymph node metastasis in proximal gastric cancer,” Annals of Surgical Oncology, vol. 16, no. 5, pp. 1304–1309, 2009. View at Publisher · View at Google Scholar · View at Scopus
  23. K. Y. Lee, S. H. Noh, W. J. Hyung et al., “Impact of splenectomy for lymph node dissection on long-term surgical outcome in gastric cancer,” Annals of Surgical Oncology, vol. 8, no. 5, pp. 402–406, 2001. View at Publisher · View at Google Scholar · View at Scopus
  24. C. M. Huang, J. B. Wang, H. S. Lu et al., “Prognostic impact of splenectomy on advanced proximal gastric cancer with No. 10 lymph node metastasis,” Chinese Journal of Surgery, vol. 14, no. 19, pp. 1483–1486, 2009. View at Google Scholar
  25. M. Ikeguchi and N. Kaibara, “Lymph node metastasis at the splenic hilum in proximal gastric cancer,” American Surgeon, vol. 70, no. 7, pp. 645–648, 2004. View at Google Scholar · View at Scopus
  26. S. P. Monig, P. H. Collet, S. E. Baldus et al., “Splenectomy in proximal gastric cancer: frequency of lymph node metastasis to the splenic hilus,” Journal of Surgical Oncology, vol. 76, no. 2, pp. 89–92, 2001. View at Google Scholar
  27. A. Csendes, P. Burdiles, J. Rojas, I. Braghetto, J. C. Diaz, and F. Maluenda, “A prospective randomized study comparing D2 total gastrectomy versus D2 total gastrectomy plus splenectomy in 187 patients with gastric carcinoma,” Surgery, vol. 131, no. 4, pp. 401–407, 2002. View at Publisher · View at Google Scholar · View at Scopus
  28. T. Sano, S. Yamamoto, and M. Sasako, “Randomized controlled trial to evaluate splenectomy in total gastrectomy for proximal gastric carcinoma: Japan clinical oncology group study JCOG 0110-MF,” Japanese Journal of Clinical Oncology, vol. 32, no. 9, pp. 363–364, 2002. View at Publisher · View at Google Scholar · View at Scopus