Additional Gastrectomy after Endoscopic Submucosal Dissection for Early Gastric Cancer Patients with Comorbidities

Table 3

A Comparison of the clinicopathologic features of gastrectomized patients with and without ESD.

Variable		With ESD (𝑛=18)	Without ESD (𝑛=64)	𝑃 value
Age (mean ± SD: year-old)		72.5±6.3	67.5±10.8	0.029
Gender				0.39
	Men	15	49
	Women	3	15
Location				0.19
	Upper	9	19
	Middle	6	22
	Lower	3	23
Tumor size (mean ± SD: mm		25.1±12.1	35.1±18.4	0.04
Gross type				0.08
	Protruding/elevated	11	21
	Flat	0	2
	Depressed/excavated	7	41
Histologic differentiation				0.012
	Well/moderately	18	48
	Poorly/signet ring cell	0	16
Depth of invasion				0.71
	sm 1	4	17
	sm 2	14	47
Node metastasis				0.63
	Positive	3	11
	Negative	15	53
Lymphatic invasion				0.52
	Positive	8	34
	Negative	10	30
Venous invasion				0.057
	Positive	5	34
	Negative	13	30
Hepatic metastasis				0.78
	Positive	0	1
	Negative	18	63
Tumor number				0.19
	Solitary	12	52
	Double or more	6	12
Preoperative comorbidities				<0.001
	Positive	18	34
	Negative	0	30
History of major abdominal surgery				0.4
	Positive	6	15
	Negative	12	49
History of gastrectomy				0.7
	Positive	1	4
	Negative	17	60
History of major extra-abdominal surgery				0.38
	Positive	3	7
	Negative	15	57
Other primary cancer				0.3
	Positive	8	20
	Negative	10	44
Surgical risk				0.012
	Positive	18	48
	Negative	0	16
Operating time (mean ± SD: min)		312.5±74.2	314.4±82.5	0.77
	Total gastrectomy	327.2±46.9	34.6±65.0	0.57
	Distal gastrectomy	304.5±86.7	293.8±86.6	0.69
Operative blood loss (mean ± SD: mL)		190.6±134.4	222.0±148.0	0.43
	Total gastrectomy	206.7±110.2	242.6±166.4	0.79
	Distal gastrectomy	181.8±150.3	208.9±135.8	0.13
Postoperative complications				0.14
	Positive	9	20
	Negative	9	44
New disorders in followup				0.074
	Positive	9	19
	Negative	9	45
Death by other diseases				0.019
	Positive	4	2
	Negative	14	62

SD, standard deviation.