Increasing Age Is Associated with Worse Prognostic Factors and Increased Distant Recurrences despite Fewer Sentinel Lymph Node Positives in Melanoma

Table 5

Multivariate model for predicting SLN positivity with age based on quartiles demonstrates a trend that increasing age is associated with decreased SLN positivity.

Variable	Hazard ratio	95% confidence interval	P value
Male	1.76	1.28–2.42	0.001
Age
<30 versus 31–40 yrs	1.01	0.56–1.85	0.96
<30 versus 41–50 yrs	0.68	0.39–1.20	0.19
<30 versus 51–60 yrs	0.75	0.43–1.31	0.31
<30 versus ≥61 yrs	0.53	0.30–0.91	0.02
Breslow depth (≥1 mm)	7.38	2.68–20.30	<0.001
Ulceration	2.13	1.54–2.94	<0.001
Head and neck site	0.80	0.53–1.22	0.31