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International Journal of Surgical Oncology
Volume 2012 (2012), Article ID 613980, 6 pages
Review Article

The Role of Secondary Surgery in Recurrent Ovarian Cancer

Fondazione IRCCS Istituto Nazionale Tumori, Via Venezian 1, 20133 Milan, Italy

Received 31 March 2012; Accepted 30 May 2012

Academic Editor: Constantine P. Karakousis

Copyright © 2012 D. Lorusso et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Despite optimal treatment (complete cytoreduction and adjuvant chemotherapy), 5-year survival for advanced ovarian cancer is approximately 30% and most patients succumb to their disease. Cytoreductive surgery is accepted as a major treatment of primary ovarian cancer but its role in recurrent disease is controversial and remains a field of discussion mainly owing to missing data from prospective randomized trials. A critical review of literature evidence on secondary surgery in recurrent ovarian cancer will be described.