Table of Contents Author Guidelines Submit a Manuscript
International Journal of Surgical Oncology
Volume 2012, Article ID 748196, 5 pages
http://dx.doi.org/10.1155/2012/748196
Review Article

Role of the Radiotherapy Boost on Local Control in Ductal Carcinoma In Situ

1Département d’Oncologie Radiothérapie, CRLC Val d’Aurelle-Paul Lamarque, 34298 Montpellier, France
2Département de Recherche Clinique, CRLC Val d’Aurelle-Paul Lamarque, 34298 Montpellier, France

Received 2 December 2011; Accepted 23 January 2012

Academic Editor: Bruno Cutuli

Copyright © 2012 Olivier Riou et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. B. A. Virnig, T. M. Tuttle, T. Shamliyan, and R. L. Kane, “Ductal carcinoma in Situ of the breast: a systematic review of incidence, treatment, and outcomes,” Journal of the National Cancer Institute, vol. 102, no. 3, pp. 170–178, 2010. View at Publisher · View at Google Scholar · View at Scopus
  2. K. Mokbel and B. Cutuli, “Heterogeneity of ductal carcinoma in situ and its effects on management,” Lancet Oncology, vol. 7, no. 9, pp. 756–765, 2006. View at Publisher · View at Google Scholar · View at Scopus
  3. I. Barillot, B. Cutuli, and L. Arnould, “Ductal in situ carcinoma: is it ethical to consider the breast conserving therapy as a standard?” Cancer/Radiotherapie, vol. 8, no. 1, pp. 9–20, 2004. View at Publisher · View at Google Scholar · View at Scopus
  4. L. A. Newman, “Local control of ductal carcinoma in situ based on tumor and patient characteristics: the surgeon's perspective,” Journal of the National Cancer Institute. Monographs, no. 41, pp. 152–157, 2010. View at Publisher · View at Google Scholar
  5. R. L. Kane, B. A. Virnig, T. Shamliyan, S.-Y. Wang, T. M. Tuttle, and T. J. Wilt, “The impact of surgery, radiation, and systemic treatment on outcomes in patients with ductal carcinoma in situ,” Journal of the National Cancer Institute. Monographs, no. 41, pp. 130–133, 2010. View at Publisher · View at Google Scholar
  6. N. Bijker and G. van tienhoven, “Local and systemic outcomes in DCIS based on tumor and patient characteristics: the radiation oncologist's perspective,” Journal of the National Cancer Institute, no. 41, pp. 178–180, 2010. View at Publisher · View at Google Scholar
  7. C. Correa, P. McGale, C. Taylor et al., “Overview of the randomized trials of radiotherapy in ductal carcinoma in situ of the breast,” Journal of the National Cancer Institute, no. 41, pp. 162–177, 2010. View at Publisher · View at Google Scholar
  8. P. Romestaing, Y. Lehingue, C. Carrie et al., “Role of a 10-Gy boost in the conservative treatment of early breast cancer: results of a randomized clinical trial in Lyon, France,” Journal of Clinical Oncology, vol. 15, no. 3, pp. 963–968, 1997. View at Google Scholar
  9. H. Bartelink, J.-C. Horiot, P. M. Poortmans et al., “Impact of a higher radiation dose on local control and survival in breast-conserving therapy of early breast cancer: 10-year results of the randomized boost versus no boost EORTC 22881-10882 trial,” Journal of Clinical Oncology, vol. 25, no. 22, pp. 3259–3265, 2007. View at Publisher · View at Google Scholar
  10. S. J. Schnitt, “Local outcomes in ductal carcinoma in situ based on patient and tumor characteristics,” Journal of the National Cancer Institute, no. 41, pp. 158–161, 2010. View at Publisher · View at Google Scholar
  11. P. Fourneret, X. Artignan, J. De Cornulier et al., “Retrospective analysis of 108 ductal carcinomas in situ of the breast treated by radiosurgery association,” Cancer/Radiotherapie, vol. 10, no. 8, pp. 550–558, 2006. View at Publisher · View at Google Scholar · View at Scopus
  12. B. Cutuli, C. Cohen-Solal-le Nir, B. De Lafontan et al., “Breast-conserving therapy for ductal carcinoma in situ of the breast: the French Cancer Centers' experience,” International Journal of Radiation Oncology Biology Physics, vol. 53, no. 4, pp. 868–879, 2002. View at Publisher · View at Google Scholar · View at Scopus
  13. L. J. Solin, A. Fourquet, F. A. Vicini et al., “Long-term outcome after breast-conservation treatment with radiation for mammographically detected ductal carcinoma in situ of the breast,” Cancer, vol. 103, no. 6, pp. 1137–1146, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. C. Tunon-de-Lara, C. Lemanski, C. Cohen-Solal-Le-Nir et al., “Ductal carcinoma in situ of the breast in younger women: a subgroup of patients at high risk,” European Journal of Surgical Oncology, vol. 36, no. 12, pp. 1165–1171, 2010. View at Google Scholar
  15. B. Fisher, J. Dignam, N. Wolmark et al., “Tamoxifen in treatment of intraductal breast cancer: national surgical adjuvant breast and bowel project B-24 randomised controlled trial,” Lancet, vol. 353, no. 9169, pp. 1993–2000, 1999. View at Publisher · View at Google Scholar · View at Scopus
  16. J.-P. Julien, N. Bijker, I. S. Fentiman et al., “Radiotherapy in breast-conserving treatment for ductal carcinoma in situ: first results of the EORTC randomised phase III trial 10853,” Lancet, vol. 355, no. 9203, pp. 528–533, 2000. View at Google Scholar
  17. N. Bijker, J. L. Peterse, L. Duchateau et al., “Risk factors for recurrence and metastasis after breast-conserving therapy for ductal carcinoma-in-situ: analysis of European Organization for Research and Treatment of Cancer Trial 10853,” Journal of Clinical Oncology, vol. 19, no. 8, pp. 2263–2271, 2001. View at Google Scholar
  18. N. Bijker, P. Meijnen, J. L. Peterse et al., “Breast-conserving treatment with or without radiotherapy in ductal carcinoma-in-situ: ten-year results of european organisation for research and treatment of cancer randomized phase III trial 10853—a study by the EORTC breast cancer cooperative group and EORTC radiotherapy group,” Journal of Clinical Oncology, vol. 24, no. 21, pp. 3381–3387, 2006. View at Publisher · View at Google Scholar
  19. C. Dunne, J. P. Burke, M. Morrow, and M. R. Kell, “Effect of margin status on local recurrence after breast conservation and radiation therapy for ductal carcinoma in situ,” Journal of Clinical Oncology, vol. 27, no. 10, pp. 1615–1620, 2009. View at Publisher · View at Google Scholar
  20. A. Ringberg, H. Nordgren, S. Thorstensson et al., “Histopathological risk factors for ipsilateral breast events after breast conserving treatment for ductal carcinoma in situ of the breast - Results from the Swedish randomised trial,” European Journal of Cancer, vol. 43, no. 2, pp. 291–298, 2007. View at Publisher · View at Google Scholar
  21. E. R. Fisher, S. R. Land, R. S. Saad et al., “Pathologic variables predictive of breast events in patients with ductal carcinoma in situ,” American Journal of Clinical Pathology, vol. 128, no. 1, pp. 86–91, 2007. View at Publisher · View at Google Scholar · View at Scopus
  22. B. Cutuli, A. Fourquet, E. Luporsi et al., “Standards, options and recommendations for the management of ductal carcinoma in situ of the breast (DCIS): update 2004,” Bulletin du Cancer, vol. 92, no. 2, pp. 155–168, 2005. View at Google Scholar · View at Scopus
  23. B. Fisher, J. Costantino, C. Redmond et al., “Lumpectomy compared with lumpectomy and radiation therapy for the treatment of intraductal breast cancer,” New England Journal of Medicine, vol. 328, no. 22, pp. 1581–1586, 1993. View at Publisher · View at Google Scholar · View at Scopus
  24. B. Fisher, S. Land, E. Mamounas, J. Dignam, E. R. Fisher, and N. Wolmark, “Prevention of invasive breast cancer in women with ductal carcinoma in situ: an update of the National Surgical Adjuvant Breast and Bowel Project experience,” Seminars in Oncology, vol. 28, no. 4, pp. 400–418, 2001. View at Google Scholar · View at Scopus
  25. I. L. Wapnir, J. J. Dignam, B. Fisher et al., “Long-term outcomes of invasive ipsilateral breast tumor recurrences after lumpectomy in NSABP B-17 and B-24 randomized clinical trials for DCIS,” Journal of the National Cancer Institute, vol. 103, no. 6, pp. 478–488, 2011. View at Publisher · View at Google Scholar
  26. J. Houghton, “Radiotherapy and tamoxifen in women with completely excised ductal carcinoma in situ of the breast in the UK, Australia, and New Zealand: randomised controlled trial,” Lancet, vol. 362, no. 9378, pp. 95–102, 2003. View at Publisher · View at Google Scholar
  27. J. Cuzick, I. Sestak, S. E. Pinder et al., “Effect of tamoxifen and radiotherapy in women with locally excised ductal carcinoma in situ: long-term results from the UK/ANZ DCIS trial,” The Lancet Oncology, vol. 12, no. 1, pp. 21–29, 2011. View at Publisher · View at Google Scholar · View at Scopus
  28. S. Emdin, B. Granstrand, A. Ringberg et al., “SweDCIS: radiotherapy after sector resection for ductal carcinoma in situ of the breast. Results of a randomised trial in a population offered mammography screening,” Acta Oncologica, vol. 45, no. 5, pp. 536–543, 2006. View at Publisher · View at Google Scholar · View at Scopus
  29. L. Holmberg, H. Garmo, B. Granstrand et al., “Absolute risk reductions for local recurrence after postoperative radiotherapy after sector resection for ductal carcinoma in situ of the breast,” Journal of Clinical Oncology, vol. 26, no. 8, pp. 1247–1252, 2008. View at Publisher · View at Google Scholar
  30. A. Omlin, M. Amichetti, D. Azria et al., “Boost radiotherapy in young women with ductal carcinoma in situ: a multicentre, retrospective study of the Rare Cancer Network,” Lancet Oncology, vol. 7, no. 8, pp. 652–656, 2006. View at Publisher · View at Google Scholar · View at Scopus
  31. P. Wong, C. Lambert, R. V. Agnihotram, M. David, M. Duclos, and C. R. Freeman, “Ductal carcinoma in situ—the influence of the radiotherapy boost on local control,” International Journal of Radiation Oncology Biology Physics, vol. 82, no. 2, pp. e153–e158, 2012. View at Publisher · View at Google Scholar
  32. M. A. Ben-David, D. E. Sturtz, K. A. Griffith et al., “Long-term results of conservative surgery and radiotherapy for ductal carcinoma in situ using lung density correction: the University of Michigan experience,” Breast Journal, vol. 13, no. 4, pp. 392–400, 2007. View at Publisher · View at Google Scholar · View at Scopus
  33. L. J. Solin, A. Fourquet, F. A. Vicini et al., “Mammographically detected ductal carcinoma in situ of the breast treated with breast-conserving surgery and definitive breast irradiation: long-term outcome and prognostic significance of patient age and margin status,” International Journal of Radiation Oncology Biology Physics, vol. 50, no. 4, pp. 991–1002, 2001. View at Publisher · View at Google Scholar · View at Scopus
  34. L. J. Solin, A. Fourquet, F. A. Vicini et al., “Salvage treatment for local or local-regional recurrence after initial breast conservation treatment with radiation for ductal carcinoma in situ,” European Journal of Cancer, vol. 41, no. 12, pp. 1715–1723, 2005. View at Publisher · View at Google Scholar
  35. E. S. Wai, M. L. Lesperance, C. S. Alexander et al., “Effect of radiotherapy boost and hypofractionation on outcomes in ductal carcinoma in situ,” Cancer, vol. 117, no. 1, pp. 54–62, 2011. View at Publisher · View at Google Scholar · View at Scopus
  36. A. Monteau, B. Sigal-Zafrani, Y. M. Kirova et al., “Ductal carcinoma in situ of the breast with close or focally involved margins following breast-conserving surgery: treatment with reexcision or radiotherapy with increased dosage,” International Journal of Radiation Oncology Biology Physics, vol. 75, no. 4, pp. 1021–1028, 2009. View at Publisher · View at Google Scholar · View at Scopus
  37. D. Azria, H. Auvray, I. Barillot et al., “Ductal carcinoma in situ: role of the boost,” Cancer/Radiotherapie, vol. 12, no. 6-7, pp. 571–576, 2008. View at Publisher · View at Google Scholar · View at Scopus