Radical Prostatectomy as a First-Line Treatment in Patients with Initial PSA  >20 ng/mL

Table 1

Patient characteristics and pathological parameters.

Parameter	Group A (𝑛=131)	Group B (𝑛=74)	𝑃 value
Patient age (years) ± SD	65.7±6.1	65.4±7.7	0.760
Mean PSA (ng/mL) ± SD	9.4±5.4	64.9±123.9	<0.001
Clinical stage (𝑛/%/)^*
cT1	32 (24.4%)	3 (4.1%)	<0.001
cT2	91 (69.5%)	43 (58.1%)	0.101
cT3-T4	8 (6.1%)	28 (37.8%)	<0.001
Gleason score (𝑛/%/)
<7	52 (39.7%)	13 (17.6%)	0.001
=7	55 (42.0%)	28 (37.8%)	0.557
>7	24 (18.3%)	33 (44.6%)	<0.001
Pathological stage (𝑛/%/)^*
pT2	89 (67.9%)	24 (32.4%)	<0.001
pT3	37 (28.2%)	42 (56.8%)	<0.001
pT4	5 (3.8%)	8 (10.8%)	0.049
Extracapsular extension (𝑛/%/)	42 (32.1%)	50 (67.6%)	<0.001
Seminal vesicles invasion (𝑛/%/)	35 (26.7%)	45 (60.8%)	<0.001
Lymph node involvement (𝑛/%/)	19 (14.5%)	35 (47.3%)	<0.001
Positive surgical margins (𝑛/%/)	20 (15.3%)	31 (41.9%)	<0.001

^*Based on TNM classification, v. 2009.