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International Journal of Surgical Oncology
Volume 2012 (2012), Article ID 921821, 8 pages
http://dx.doi.org/10.1155/2012/921821
Review Article

Oncologic Safety of Skin-Sparing and Nipple-Sparing Mastectomy: A Discussion and Review of the Literature

1Department of Surgery, University of San Diego, San Diego, CA 92103, USA
2Department of Pathology, University of San Diego, San Diego, CA 92103, USA

Received 23 February 2012; Revised 6 June 2012; Accepted 7 June 2012

Academic Editor: Kefah Mokbel

Copyright © 2012 Christopher Tokin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Breast conservation therapy has been the cornerstone of the surgical treatment of breast cancer for the last 20 years; however, recently, the use of mastectomy has been increasing. Mastectomy is one of the most frequently performed breast operations, and with novel surgical techniques, preservation of the skin envelope and/or the nipple-areolar complex is commonly performed. The goal of this paper is to review the literature on skin-sparing mastectomy and nipple-sparing mastectomy and to evaluate the oncologic safety of these techniques. In addition, this paper will discuss the oncologic importance of margin status and type of mastectomy as it pertains to risk of local recurrence and relative need for adjuvant therapy.