Are the American Society for Radiation Oncology Guidelines Accurate Predictors of Recurrence in Early Stage Breast Cancer Patients Treated with Balloon-Based Brachytherapy?

Table 4

Surgical management of ipsilateral breast tumor recurrences.

Case no.	Date of surgery	Time to IBTR (yrs)	Location	ASTRO criteria	Surgical management	Radiation therapy	Follow-up time (yrs)	Disease status
22	2005	3.99	Elsewhere	ER negative, close margin	Mastectomy	No	5.21	NED
44	2005	3.13	Elsewhere	ER negative	Mastectomy	No	5.33	NED
50	2005	5.83	Local	Age 50–59, DCIS ≤ 3 cm, and ER negative	Segmental resection	No^a	5.81	NED
71	2006	2.64	Elsewhere	Age < 50, close margin, and DCIS ≤ 3 cm	Mastectomy	No	5.16	DOD
91.1^b	2007	3.82	Elsewhere	ER negative, close margin, and tumor size 2.1–3.0 cm	Segmental resection	No^c	3.95	NED
107	2006	1.45	Elsewhere	Positive margin, multifocal 2.1–3.0 cm	Segmental resection	Yes	4.52	NED
147	2007	2.73	Elsewhere	Close margin	Segmental resection	Yes^d	3.50	NED
208	2009	1.21	Elsewhere	Close margin, age 50–59, and DCIS ≤ 3 cm	Segmental resection	No^c	1.56	NED

ER: estrogen receptor, NED: no evidence of disease, DCIS: ductal carcinoma in situ, and DOD: dead of disease.
aPatient is currently receiving chemotherapy. Decision for radiation was undetermined at the completion of the study.
bPatient tested positive for deleterious mutation in BRCA gene following recurrence.
cPatient declined radiation therapy.
dRecurrence treated with APBI via balloon catheter brachytherapy.