Research Article

Now, Later of Never: Multicenter Randomized Controlled Trial Call—Is Surgery Necessary after Atypical Breast Core Biopsy Results in Mammographic Screening Settings?

Table 2

Secondary outcome: comparison of mastectomy rates.

MastectomyComparison (current surgical management)Intervention arm (conservative management)

Yes
No

The principles of statistical analysis of mastectomy rates difference are similar to the primary outcomes (i.e., relative risk, absolute risk reduction, and number needed to treat).