International Journal of Surgical Oncology / 2015 / Article / Tab 4

Review Article

Gastrectomy and D2 Lymphadenectomy for Gastric Cancer: A Meta-Analysis Comparing the Harmonic Scalpel to Conventional Techniques

Table 4

Summary of primary and sensitivity analyses.

Operating time (min)
(MD [95% CI])
Intraoperative blood loss (mL)
(MD [95% CI])
Drainage volume (mL)
(MD [95% CI])
LOS (days)
(MD [95% CI])
Complications ()
(RR [95% CI])
Patient transfusions ()
(RR [95% CI])

Primary analysis−27.50 (−42.20, −12.81)−93.15 (−125.29, −61.00)−138.83 (−177.57, −100.10)−0.63 (−2.48, 1.23)0.58 (0.33, 1.02)0.68 (0.38, 1.19)

Sensitivity analyses

Excluding “lower” quality studies (Tsimoyiannis et al., 2002 [28], Chen, 2012 [20], and Inoue et al., 2012 [26])−28.66 (−49.47, −7.85)−79.20 (−118.09, −40.32)−126.00 (−161.92, −90.08)Too few studies (<2) to inform0.41 (0.18, 0.92)Too few studies (<2) to inform

Only monopolar electrosurgery (i.e., excluding suture ligation)−45.15 (−58.96, −31.33)−91.59 (−137.55, −45.62)−93.55 (−114.08, −73.02)Too few studies (<2) to informToo few studies (<2) to informToo few studies (<2) to inform

Excluding imputed data
(Inoue et al., 2012 [26], Wilhelm, 2011 [23], and Lu et al., 2008 [24])
−27.62 (−43.84, −11.41)−91.92 (−124.39, −59.45)−157.39 (−196.50, −118.27)−1.07 (−4.53, 2.40)0.58 (0.33, 1.02)0.68 (0.38, 1.19)

CI: confidence interval; LOS: length of stay; MD: mean difference; RR: relative risk.
Lower quality study defined as ≥4 “unclear” or one “No” listed in any risk of bias assessment category.

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