Clear Cell Adenocarcinoma of the Urethra: Review of the Literature

Figure 12

This figure shows architectural patterns of clear cell adenocarcinomas and granular cytoplasmic reactivity with P504S. (a) Tubulocystic pattern with tubules lined by cells with clear cytoplasm component (bladder case 1). (b) Positive staining with P504S bladder case 1). (c) Diffuse growth of clear cells (bladder, case 2). (d) Positive staining with P504S (bladder, case 2). (e) Tubulocystic pattern with tubules lined by hobnail cells showing moderate to severe nuclear atypia (urethra, case 3). (f) Positive staining with P504S (urethra, case 3). (g) Papillary growth pattern with papillae lined by hobnail cells with severe nuclear atypia and mitoses (urethral diverticulum, case 4). (h) Positive staining with P504S (urethral diverticulum, case 4). Haematoxylin-eosin and immunoperoxidase original magnification ×200. Reprinted from [8] Sun et al. Clear cell adenocarcinoma of the urinary bladder and urethra: another urinary tract lesion immunoreactive for P504S. Arch Pathol Lab Med 2008 Sep; 132(9): 1417–1422 reprinted with permission from Archives of Pathology and Laboratory Medicine Copyright 2008 College of American Pathologists. This permission is exclusive to this request specifically for this paper. Additional usage of any printed or electronic material for which the Archives of Pathology and Laboratory Medicine owns copyright would require permission from the editorial office.

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