Neoadjuvant Chemotherapy in Locally Advanced and Borderline Resectable Nonsquamous Sinonasal Tumors (Esthesioneuroblastoma and Sinonasal Tumor with Neuroendocrine Differentiation)

Table 2

Extent of locoregional spread.

Extent	Esthesioneuroblastoma; ( patients)	SN-NEC; ( patients)	Total; (25 patients)
Involvement of cribriform plate	12 (100.0%)	13 (100.0%)	25 (100.0%)
Intracranial extension up to extradural region	06 (50.0%)	08 (61.5%)	14 (56%)
Intradural intracranial extension but brain parenchyma uninvolved	06 (50.0%)	04 (30.8%)	10 (40%)
Intradural extension with brain parenchyma involvement	02 (16.7%)	03 (23.1%)	05 (20%)
Involvement of orbit	06 (50.0%)	07 (53.8%)	13 (52%)
Involvement of infratemporal fossa	03 (25%)	03 (23.1%)	06 (24%)
Involvement of parapharyngeal space	01 (08.3%)	01 (7.7%)	02 (08%)
Involvement of regional lymph nodes	03 (25%)	05 (38.5%)	08 (32%)