Survival Benefit of Intervention Treatment in Advanced Anaplastic Thyroid Cancer

Figure 3

Thirty-seven ATC patients in stage IVa had a median survival time of 118 days (95% CI: 54–160) in the interventional treatment group, whereas the palliative treatment group had a median survival time of 33 days (95% CI: 10–46). This difference was statistically significant (). The Kaplan-Meier curve showed the benefit survival rate in the intervention group (log-rank test; ) (a). In 39 patients with ATC stage IVb, the interventional treatment allowed a median survival time of 110 days (95% CI: 64–177), which was better than palliative treatment (median survival time: 63 days (95% CI: 49–133)); however, the median time survival difference was not statistically significant (). The Kaplan-Meier curve showed that the intervention group seemed superior to palliative treatment but did not reach statistical significance (log-rank test; ) (b). Regarding the median survival time of 29 patients with ATC stage IVc, the intervention group (96 days (95% CI: 10–168)) was not significantly better than the palliative group (64 days (95% CI: 37–93)) (). However, the Kaplan-Meier survival curve of the intervention group was not significantly better than that of the palliative group (log-rank test; ) (c).

(a)

(b)

(c)