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International Journal of Vascular Medicine
Volume 2010 (2010), Article ID 134692, 5 pages
Clinical Study

Gender Differences of Plaque Characteristics in Elderly Patients with Stable Angina Pectoris: An Intravascular Ultrasonic Radiofrequency Data Analysis

1Cardiovascular Division, Saitama Citizens Medical Center, 299-1 Shimane, Nishi-ku, Saitama 331-0054, Japan
2Cardiovascular Division, Saitama Medical Center, Jichi Medical University, Saitama, Japan

Received 17 May 2010; Accepted 1 December 2010

Academic Editor: Albert G. Hakaim

Copyright © 2010 Tomohiro Nakamura et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The purpose of this study was to evaluate the relation between gender and plaque characteristics assessed by virtual histology-intravascular ultrasound (VH-IVUS) in patients with stable angina pectoris. Preinterventional VH-IVUS image was available for analysis in 88 men and 60 women patients. Women had significantly smaller vessel volume (12.7 ± 3.9 versus 14.5 ± 4.2 mm3/mm, ) and smaller plaque volume (8.4 ± 3.5 versus 9.7 ± 3.5 mm3/mm, ). However, these differences were no longer significant when corrected for body surface area (BSA). In VH-IVUS analysis, women had significantly higher dense calcium when corrected for BSA in the culprit lesion (volume: 0.32 ± 0.26 versus 0.44 ± 0.40 mm3/mm/BSA, ; proportion: 8.2 ± 6.1 versus 11.2 ± 7.6%, ). VH-IVUS analysis of plaque components in elderly patients with stable angina showed that women had higher calcium contents compared with men.