Peripheral Arterial Disease in Patients Presenting with Acute Coronary Syndrome in Six Middle Eastern Countries
Table 4
Risk factors and outcomes of peripheral arterial disease in patients presenting with acute coronary syndrome in different studies.
SPRINT 1994
GRACE 2007
PAMISCA 2008
MASCARA 2009
Gulf RACE 2009
Patients .
4258
32735
1410
6745
6705
PAD prevalence
6.3%
7.6%
39.8%
8.8%
2.4%
PAD
No PAD
value
PAD
No PAD
value
PAD
No PAD
value
PAD
No PAD
value
PAD
No PAD
value
Age (years)
66 ± 10
62 ± 11
0.01
71
64
0.001
69 ± 11.3
64 ± 11
0.001
70 ± 10
67 ± 10
0.001
65 ± 11
56 ± 12
0.001
Diabetes mellitus
25
20
0.01
38
22
0.001
41.5
30.6
0.001
49.4
28.1
0.001
70
40
0.001
Hypertension
47
39
0.01
72
58
0.001
84.1
76.1
0.001
71.9
58.3
0.001
Dyslipidemia
—
—
—
58
46
0.001
85.7
83
NS
57
46.4
0.001
66
31
0.001
Smoking
35
36
NS
69
59
0.001
29.9
31.6
NS
21.6
28.3
0.001
32
38
0.001
Hospital outcome
Death
24
13
0.001
7.2
4.5
0.001
2
0.2
0.001
9.1
4.8
0.001
8
4
0.002
CHF
23
19
NS
—
—
—
15.9
8.4
0.001
—
—
—
31
16
0.001
Re-ischemia/infarction
—
—
—
7.7
8.3
NS
13.7
7.8
0.001
—
—
—
14
10
0.03
SPRINT: Secondary Prevention Study Reinfarction Israeli Nifedipine Trial, GRACE: Global Registry of Acute Coronary Events. PAMISCA: Prevalencia de Afectación de Miembros Inferiores en el paciente con Síndrome Coronario Agudo, MASCARA: Manejo del Sindrome Coronario Agudo. Registro Actualizado, Gulf RACE: Gulf Register of Acute Coronary Events, CHF: congestive heart failure. [1, 11, 14, 15].
