A Model of Left Ventricular Dysfunction Complicated by CAWS Arteritis in DBA/2 Mice

<table>Kaplan-Meier analysis of CAWS arteritis in DBA/2 mice. CAWS treatment DBA/2 mice were administered with CAWS one mg/mouse via peritoneal injections for five consecutive days. DBA/2 mice at four or five weeks of age were maintained in specific pathogen free (SPF) conditions and observed every day. All CAWS treatment mice died between five and eight weeks after treatment. <svg height="11.375" id="M6" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 66.875 11.375" width="66.875" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,11.112)"><use xlink:href="#x1D443"></use></g><g transform="matrix(.017,-0,0,-.017,15.582,11.112)"><use xlink:href="#x3C"></use></g><g transform="matrix(.017,-0,0,-.017,30.286,11.112)"><use xlink:href="#x30"></use></g><g transform="matrix(.017,-0,0,-.017,38.446,11.112)"><use xlink:href="#x2E"></use></g><g transform="matrix(.017,-0,0,-.017,42.321,11.112)"><use xlink:href="#x30"></use></g><g transform="matrix(.017,-0,0,-.017,50.481,11.112)"><use xlink:href="#x30"></use></g><g transform="matrix(.017,-0,0,-.017,58.64,11.112)"><use xlink:href="#x35"></use></g>
</svg> for survival of untreated versus CAWS treatment mice at six weeks after the CAWS treatment; <svg height="11.125" id="M7" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 36.237499 11.125" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,10.862)"><use xlink:href="#x1D45B"></use></g><g transform="matrix(.017,-0,0,-.017,13.305,10.862)"><use xlink:href="#x3D"></use></g><g transform="matrix(.017,-0,0,-.017,28.008,10.862)"><use xlink:href="#x38"></use></g>
</svg> (control) and <svg height="11.125" id="M8" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 44.400002 11.125" width="44.400002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,10.862)"><use xlink:href="#x1D45B"></use></g><g transform="matrix(.017,-0,0,-.017,13.305,10.862)"><use xlink:href="#x3D"></use></g><g transform="matrix(.017,-0,0,-.017,28.008,10.862)"><use xlink:href="#x31"></use></g><g transform="matrix(.017,-0,0,-.017,36.168,10.862)"><use xlink:href="#x30"></use></g>
</svg> (CAWS treatment).</table>

International Journal of Vascular Medicine

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Figure 1

Figure 1: A Model of Left Ventricular Dysfunction Complicated by CAWS Arteritis in DBA/2 Mice 