Review Article

The Chylomicron: Relationship to Atherosclerosis

Figure 2

Chylomicron clearance. The chylomicron acquires apo E and apo C111 in the circulation, and most of the triglyceride is hydrolised by lipoprotein lipase (LPL) prior to it being cleared by the low density lipoprotein (LDL) B/E receptor or the LDL receptor-related protein (LRP) receptor in the liver. GPIHB also plays a smaller part in uptake of chylomicron remnants by the liver capillaries.