International Journal of Vascular Medicine

Research Article

Cost-Effectiveness of Catheter Ablation for Rhythm Control of Atrial Fibrillation

Table 4

One-way sensitivity analyses.
 Incremental costsIncremental QALYsIncremental $/QALY
Sensitivity analysis by age and gender assuming the same risk of stroke for all starting ages
Males   
 Age   
  55$8,330 0.146 $57,167
  60$8,365 0.145 $57,846
  65$8,539 0.144 $59,194
  70$8,630 0.141 $61,120
  75$8,787 0.135 $65,129
Females   
 Age   
  55$8,330 0.146 $57,088
  60$8,365 0.145 $57,765
  65$8,548 0.144 $59,219
  70$8,637 0.141 $61,142
  75$8,793 0.135 $65,147
CHADS2 risk score   
 0$9,259 0.135 $68,822
 1$8,941 0.139 $64,412
 2$8,539 0.144 $59,194
 3$7,952 0.152 $52,214
 4$7,242 0.162 $44,652
Time horizon   
 3 years$10,670 0.082 $130,711
 5 years$8,539 0.144 $59,194
 10 years$4,299 0.301 $14,273
 20 years($71)0.505 AF ablation dominates
Discount rate   
 0%$7,995 0.162 $49,308
 3%$8,335 0.151 $55,211
 5%$8,539 0.144 $59,194
 Restoring NSR has no impact on stroke risk$10,019 0.116 $86,129
Disutility of AF health state   
 0$8,539 0.038 $221,839
 0.02$8,539 0.084 $101,083
 0.04$8,539 0.130 $65,454
 0.06$8,539 0.176 $48,396
 0.08$8,539 0.222 $38,390
Annual probability of recurrence of AF after ablation   
 0.00$8,230 0.153 $53,831
 0.01$8,317 0.150 $55,276
 0.02$8,403 0.148 $56,743
 0.03$8,486 0.146 $58,233
 0.04$8,569 0.143 $59,745
 0.05$8,650 0.141 $61,280