Clinical Study

Gene Expression of Adhesion Molecules in Endothelial Cells from Patients with Peripheral Arterial Disease Is Reduced after Surgical Revascularization and Pharmacological Treatment

Table 1

Clinical characteristics of PAD patients at enrollment. Values are means ± SD.

PAD patients: 9
 Sex: 2 females (22,3%); 7 males (77,7%)
 Age, years: 68,0 ± 8,5

Rutherford classification
 Stage 0–2: 0
 Stage 3: 3 (33,3%)
 Stage 4: 4 (44,4%)
 Stage 5: 2 (22,2%)
 Stage 6: 0

Pharmacological treatment
 Antiplatelet drugs: 8 (88,8%)
 ACE inhibitors: 5 (55,5%)
 Ca++-channel blockers: 7 (77,7%)
 Hypoglycaemic drugs: 1 (11,1%)
 Other drugs: 7 (77,7%)

Clinical notes
 Smokers: 5 (55,5%)
 Alcohol users: 2 (22,2%)
 Diabetes: 2 (22,2%)
 Hypertension*: 8 (88,8%)
 Hypercholesterolemia*: 7 (77,7%)
 Atrial fibrillation: 1 (11,1%)
 Ictus: 1 (11,1%)

Hypertension and hypercholesterolemia were defined as indicated by National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure, National High Blood Pressure Education Program Coordinating Committee [8].