International Journal of Vascular Medicine / 2013 / Article / Tab 1

Research Article

Etanercept Suppresses Arteritis in a Murine Model of Kawasaki Disease: A Comparative Study Involving Different Biological Agents

Table 1

Animal data. Body weight (BW), heart weight (HW), and HW/BW ratio (%) in each group at 2 and 4 weeks.

ConCAWSIVIGECMPCsA

2 weeks
( for each group)
Body weight (g)21.7 ± 1.120.9 ± 0.119.2 ± 0.121.3 ± 0.119.7 ± 0.118.8 ± 0.1
Heart weight (g) 0.14 ± 0.04 0.13 ± 0.02 0.12 ± 0.02 0.13 ± 0.01 0.12 ± 0.01 0.12 ± 0.01
HW/BW (%)0.62 ± 0.1 0.60 ± 0.06 0.60 ± 0.05 0.61 ± 0.04 0.59 ± 0.01 0.62 ± 0.08

4 weeks
( for each group)
Body weight (g)22.2 ± 0.1420.9 ± 0.222.8 ± 0.121.4 ± 0.119.5 ± 0.122.4 ± 0.1
Heart weight (g)0.14 ± 0.01 0.18 ± 0.02 0.14 ± 0.02 0.15 ± 0.02 0.13 ± 0.01 0.13 ± 0.03
HW/BW (%)0.63 ± 0.06 0.86 ± 0.07# 0.59 ± 0.07 0.68 ± 0.07 0.68 ± 0.05 0.57 ± 0.14

versus Con.
Abbreviations: control (Con), CAWS with no drug treatment (CAWS), immunoglobulin (IVIG), etanercept (EC), methylprednisolone (MP), and cyclosporine-A (CsA).