Purpurogallin, a Natural Phenol, Attenuates High-Mobility Group Box 1 in Subarachnoid Hemorrhage Induced Vasospasm in a Rat Model

Figure 4

HMRB1 mRNA expression on 48 hr after first SAH and 72 hr after second SAH, respectively (rt-PCR). All groups are identical to those shown in the legends of Figure 3. ; : represents purpurogallin treatment (48 hr after first SAH); purpurogallin dose-dependently (72 hr after second SAH) attenuated HMGB1 mRNA transcription, when compared with the SAH groups.