Changes in Cardiopulmonary Reserve and Peripheral Arterial Function Concomitantly with Subclinical Inflammation and Oxidative Stress in Patients with Heart Failure with Preserved Ejection Fraction

Table 3

Correlations between biomarkers and peak VO₂ for the study population.

	Peak VO2	HRR 2	BNP	hsCRP	IL-6	8-epi-PG-F2𝛼	TBARS
Pearson correlation coefficients (𝑃 values)
Peak VO2	1
HRR 2	0.71***	1
BNP	−0.66***	−0.57***	1
hsCRP	−0.40*	−0.49**	0.45*	1
IL-6	−0.63***	−0.57***	0.70***	0.67***	1
8-epi-PG-F2𝛼	−0.41*	−0.38*	0.44*	0.21	0.55**	1
TBARS	−0.22	−0.19	0.26	0.39*	0.41*	0.43*	1

BNP: brain natriuretic peptide; HRR2: heart rate recovery at 2 min following the end of exercise; hsCRP: high-sensitivity C-reactive protein; IL-6: interleukin-6; TBARS: thiobarbituric acid reactive substances; VO₂: oxygen consumption; 8-epi-PG-F2𝛼: 8-epi-prostaglandin F2𝛼. *𝑃<0.05; **𝑃<0.01; ***𝑃<0.001.