International Journal of Vascular Medicine / 2015 / Article / Tab 6

Research Article

A Comparison of the Efficacy and Cost of Different Venous Leg Ulcer Dressings: A Retrospective Cohort Study

Table 6

Some of the factors that affect wound healing [15].

Systemic factors which impair wound healingLocal factors which impair wound healing

Inadequate oxygenation
Increased BMI
Increased age
Sex hormones: aged males have been shown to have delayed healing
Psychosocial stress causing delayed healing
Comorbidities, heart disease, TIA, and diabetes
Glucocorticoids, immunosuppressants, and NSAIDs
Chemotherapy and anticoagulants
Alcohol consumption impairing wound healing
Smoking impairing wound healing
Deficiency of carbohydrates, proteins, vitamins A, B, and C, iron, zinc, copper, and magnesium
Infection and pus
Necrotic tissue and foreign bodies
Dry wound
Mechanical stress on wound
Cold environmental temperature
Local oxygenation: this is decreased in peripheral vascular disease, previous radiation, inflammation, and diabetes mellitus

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