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International Journal of Vascular Medicine
Volume 2015, Article ID 265670, 5 pages
Research Article

Favorable Outcomes after Implantation of Biodegradable Polymer Coated Sirolimus-Eluting Stents in Diabetic Population: Results from INDOLIMUS-G Diabetic Registry

1Lalitha Super Speciality Hospital (P) Ltd., Heart and Brain Centre, Kothapet, Guntur, Andhra Pradesh 522001, India
2Apollo Hospitals, Plot No. 1 A, Bhat GIDC Estate, Gandhinagar, Gujarat 382428, India
3Yashfeen Cardiac Hospital, Navsari, Gujarat 396445, India
4Lions Sterling Super Specialty Hospital, Mehsana, Gujarat 384001, India
5Department of Clinical Trials, Sahajanand Medical Technologies Pvt. Ltd., Surat, Gujarat 395004, India

Received 9 July 2015; Revised 20 August 2015; Accepted 20 August 2015

Academic Editor: John A. Kern

Copyright © 2015 Anurag Polavarapu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. The main aim is to evaluate safety, efficacy, and clinical performance of the Indolimus (Sahajanand Medical Technologies Pvt. Ltd., Surat, India) sirolimus-eluting stent in high-risk diabetic population with complex lesions. Methods. It was a multicentre, retrospective, non-randomized, single-arm study, which enrolled 372 diabetic patients treated with Indolimus. The primary endpoint of the study was major adverse cardiac events (MACE), which is a composite of cardiac death, target lesion revascularization (TLR), target vessel revascularization (TVR), myocardial infarction (MI), and stent thrombosis (ST). The clinical follow-ups were scheduled at 30 days, 6 months, and 9 months. Results. The mean age of the enrolled patients was 53.4 ± 10.2 years. A total of 437 lesions were intervened successfully with 483 stents (1.1 ± 0.3 per lesion). There were 256 (68.8%) male patients. Hypertension and totally occluded lesions were found in 202 (54.3%) and 45 (10.3%) patients, respectively. The incidence of MACE at 30 days, 6 months and 9 months was 0 (0%), 6 (1.6%), and 8 (2.2%), respectively. The event-free survival at 9-month follow-up by Kaplan Meier method was found to be 97.8%. Conclusion. The use of biodegradable polymer coated sirolimus-eluting stent is associated with favorable outcomes. The results demonstrated in our study depict its safety and efficacy in diabetic population.