International Journal of Vascular Medicine / 2017 / Article / Tab 2

Research Article

Circulating Angiogenic Growth Factors in Diabetes Patients with Peripheral Arterial Disease and Exertional Leg Pain in Ghana

Table 2

Clinical characteristics of study participants by PAD status.

CharacteristicsAll participants ()Non-PAD ()PAD ()

Age, years0.062
Female, (%)127 (50.8)98 (47.1)17 (40.5)0.142
Diabetes, (%)140 (56)106 (51)34 (80.9)0.002
Hypertension, (%)152 (60.8)116 (55.8)36 (85.7)<0.001
Leg pains62 (24.8)40 (19.2)22 (52.4)<0.001
Alcohol intake, (%)12 (4.8)4 (1.9)8 (19)<0.001
Previous smokers, (%)47 (18.8)22 (10.6)25 (59.5)<0.001
Body height, cm0.699
BMI, kg/m20.735
Body fat, %0.318
Visceral fat, %0.301
Waist circumference, cm0.321
Waist-hip ratio0.287
Systolic BP, mm Hg0.629
Diastolic BP, mm Hg0.124
Pulse BP, mm Hg0.027
Mean BP, mm Hg0.06
Heart rate, bpm0.937
FPG, mmol/L0.673
2 h PPG, mmol/L0.221
Total cholesterol, mmol/L0.981
Triglycerides, mmol/L0.626
HDL, mmol/L0.695
LDL, mmol/L0.642
eGFR ml/min/1.73 m282.4 (73.1–104.9)86.3 (72.2–106.1)80.9 (71.4–101.8)0.542
Low eGFR, (%)43 (17.2)32 (15.4)11 (26.2)0.095
Vascular growth factors
Ang-1, ng/ml38.3 (25.7–47.9)40.9 (28.2–62.1)31.3 (24.8–42.6)0.017
Ang-2, pg/ml739.7 (391.7–1106.9)732.2 (391.7–1098.8)858.8 (416.7–1559.2)0.174
VEGF-A, pg/ml63 (21–158)57.7 (16.6–161.1)85.8 (37.5–154.5)0.032
Ang-1/246.3 (27.6–90.6)48.8 (29.7–93)38.9 (20.9–69.7)0.081

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