Review Article

Segmental Arterial Mediolysis: A Multiguised Vasospastic Arteriopathy with Collateral Mesangial Cell Hyperplasia and Cardiac Toxicity Generated by Norepinephrine and Hyperdense Adrenoceptors Alone or by Crosstalk with Other Pressor Agents

Figure 13

Segmental arterial mediolysis injurious phase. The red arrow points to a medial island, situated between two fibrin-lined gaps (black arrows), showing early detachment provoked by hemorrhage from injured granulation tissue in the outer media and adventitial-medial junction. Hematoxylin & eosin ×100 (adapted with permission from the International Journal of Surgical Pathology 15(2) copyright 200, Sage Publications, Inc.).