Segmental Arterial Mediolysis: A Multiguised Vasospastic Arteriopathy with Collateral Mesangial Cell Hyperplasia and Cardiac Toxicity Generated by Norepinephrine and Hyperdense Adrenoceptors Alone or by Crosstalk with Other Pressor Agents

Figure 24

Segmental arterial mediolysis reparative phase evolved to FMD with intramural hematomas. The black arrow points to a large zone of granulation tissue expanding the tear space and reoccupying areas of lost media. The white arrows point to two hematomas generated in the granulation tissue. The red arrows point to two foci of transmedial granulation tissue bordering a central medial island. Movat stain ×25 (adapted with permission from Cardiovascular Pathology 18(6) copyright 2009, Elsevier Inc.).