Segmental Arterial Mediolysis: A Multiguised Vasospastic Arteriopathy with Collateral Mesangial Cell Hyperplasia and Cardiac Toxicity Generated by Norepinephrine and Hyperdense Adrenoceptors Alone or by Crosstalk with Other Pressor Agents

Figure 31

Vasospastic venous angiopathy. Medial muscle showing confluent mediolysis distributed in an edematous background containing membranous and organelle remnants, a few intact muscle cells some with cytoplasmic vacuoles, and scattered apoptotic bodies. Hematoxylin & eosin ×200 (adapted with permission from the International Journal of Surgical Pathology 15(2) copyright 2007, Sage Publication).