Review Article

Segmental Arterial Mediolysis: A Multiguised Vasospastic Arteriopathy with Collateral Mesangial Cell Hyperplasia and Cardiac Toxicity Generated by Norepinephrine and Hyperdense Adrenoceptors Alone or by Crosstalk with Other Pressor Agents

Figure 8

Segmental arterial mediolysis injurious phase. Arrow points to an adventitial-medial tear site outwardly delineated by a linear layer of fibrin. Tear space is edematous and contains fibrin strands and red cells. Fibroblasts and occasional leukocytes are evident in the adjacent adventitial tissue. Hematoxylin & eosin ×100 (adapted with permission from Modern Pathology 8(3) copyright 1995, Nature Publishing Group).