Segmental Arterial Mediolysis: A Multiguised Vasospastic Arteriopathy with Collateral Mesangial Cell Hyperplasia and Cardiac Toxicity Generated by Norepinephrine and Hyperdense Adrenoceptors Alone or by Crosstalk with Other Pressor Agents

<div>Segmental arterial mediolysis injurious phase. Pig renal artery showing a circumferential separation of the outer media from the adventitia. An edematous tear space containing fibrin strands outwardly pushes the adventitia away from the media. PAS stain ×100 (adapted with permission from Veterinary Pathology 52(6), copyright 2015, Sage Publications Inc.).</div>

International Journal of Vascular Medicine

fig9

Figure 9

Figure 9: Segmental Arterial Mediolysis: A Multiguised Vasospastic Arteriopathy with Collateral Mesangial Cell Hyperplasia and Cardiac Toxicity Generated by Norepinephrine and Hyperdense Adrenoceptors Alone or by Crosstalk with Other Pressor Agents 

Figure 9 | Segmental Arterial Mediolysis: A Multiguised Vasospastic Arteriopathy with Collateral Mesangial Cell Hyperplasia and Cardiac Toxicity Generated by Norepinephrine and Hyperdense Adrenoceptors Alone or by Crosstalk with Other Pressor Agents 