Cardio- and cerebrovascular diseases are the major causes of death worldwide. Accumulating evidence has revealed that inflammation plays a pivotal role in the progression of vascular remodeling and atherosclerosis leading to cardiovascular events. In fact, several inflammatory markers such as a high-sensitivity C-reactive protein have been shown to predict cardiovascular events. In addition, metabolic disorders, including hyperglycemia, hyperinsulinemia, and dyslipidemia, injure the vascular wall and contribute to the development of vascular remodeling. Most of these metabolic stimuli initially impair homeostasis of the cardiovascular system through inflammation with recruitment of leukocytes and increased secretion of adhesion molecules, chemoattractant cytokines, and proinflammatory cytokines from endothelial cells, vascular smooth muscles, fibroblasts, and macrophages.

In this special issue, we are going to invite front-line researchers and authors to submit original research and review articles that explore the interactions between inflammation and vascular remodeling. Therefore, we are interested in articles that provide pivotal and/or novel evidence for understanding the pathophysiological relationships among the disorders and propose new strategies for treating these conditions on a clinical basis and a molecular basis. Potential topics include, but are not limited to:

• Aberrant circadian rhythm and vascular inflammation
• Adipocyte-secreted factors for interaction of inflammation and atherosclerosis
• Role of inflammation and oxidative stress
• Interactions of some remote organs and cardiovascular inflammation (central nervous system, digestive organs, cardiovascular system, fat tissue, etc.)
• Vascular inflammation and renin-angiotensin system
• Available biomarkers for linkage of inflammation and atherosclerosis
• Pathophysiological roles of inflammation in angiogenesis

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ijvm/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable: