Studies on the Pinctada fucata BMP-2 Gene: Structural Similarity and Functional Conservation of Its Osteogenic Potential within the Animal Kingdom
Figure 1
Dotlet comparison of PfBMP-2 and other homologs. (a) Comparison of PfBMP-2 with hBMP-2; (b) comparison of PfBMP-2 with Drosophilidae 60A; (c) comparison of PfBMP-2 with Drosophilidae Dpp; (d) comparison of PfBMP-2 with Xenopus BMP-2; (e) comparison of PfBMP-2 with AmphiBMP2/4; (f) comparison of hBMP-2 with Drosophilidae Dpp; (g) comparison of hBMP-2 with AmphiBMP2/4. The total number of amino acids is shown numerically. The thin lined arrow indicates the direction of the amino acid sequence from the N- to the C-terminus. Abbreviations with GenBank accession number in parentheses; hBMP-2: human BMP-2 (NM001200); PfBMP-2: Pinctada fucata BMP-2 (AB176952); Drosophilidae 60A: Drosophila transforming growth factor B-like protein (M77012); Dpp: Drosophila decapentaplegic protein (AF041439); Xenopus BMP-2: Xenopus laevis BMP-2 (NM001101666); AmphiBMP2/4: Branchiostoma floridae bone morphogenetic protein 2/4 (AF068750). Dotlet was performed at http://myhits.isb-sib.ch/cgi-bin/dotlet [17].
