Interdisciplinary Perspectives on Infectious Diseases / 2009 / Article / Fig 6

Review Article

Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs

Figure 6

Trypanosoma cruzi epimastigotes treated with ketoconazole, an inhibitor of the C -demetilase (a)-(b), and L. amazonensis promastigotes treated with E5700, an inhibitor of the squalene synthase (c) showing an intense mitochondrial swelling (a)-(b) and alterations in the kinetoplast structure ((c), arrowhead). K, kinetoplast; M, mitochondrion. (a)-(b) Images are reproduced with permission from [74] American Society for Microbiology. Bars, m.
642502.fig.006a
(a)
642502.fig.006b
(b)
642502.fig.006c
(c)

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