Interdisciplinary Perspectives on Infectious Diseases / 2009 / Article / Fig 9

Review Article

Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs

Figure 9

(a) Diferential interference contrast (DIC) microscopy and (b) transmission electron microscopy showing the presence of a prominent contractile vacuole (arrows) near the flagellar pocket after treatment of L. amazonensis promastigotes with quinuclidine inhibitors. In the left panel it is possible to observe a rounded and swollen parasite that probably indicates osmotic changes due alterations in the plasma membrane’s permeability. F, flagellum; K, kinetoplast. Bars, m and m, respectively.

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