Changes Related to Age in Natural and Acquired Systemic Self-IgG Responses in Malaria
Figure 2
Identification of antigenic bands discriminating MEIs with or without neurological manifestations and NECs. (a) Schematic representation of 1 western-blot strip, showing the 8 healthy brain antigenic bands (characterized by their molecular weight) that reveal discriminatory immune reactivities with sera from MEI with or without neurological manifestations and NEC. The coefficient values assigned by linear discriminant analysis (LDA; coefficients for the axis and axis) are specified for each antigenic band. (b) Graphic extrapolation of the LDA data, obtained from the plasma tests of the 3 clinical groups of subjects revealed three distinct zones in which the NEC subjects were clearly separate from MEI.
