Interdisciplinary Perspectives on Infectious Diseases / 2013 / Article / Tab 4

Clinical Study

Utility of Serum Neopterin and Serum IL-2 Receptor Levels to Predict Absolute CD4 T Lymphocyte Count in HIV Infected Cases

Table 4

Measures of validity and roc curve area of neopterin and sIL-2R in relation to the CD4 cell count <200 cells/μL.

Measures of validityS. neopterin (95% CI) sIL-2R (95% CI)

Cutoff value>25.1 nmol/L>47.1 pM
Sensitivity90.9
(95% CI: 70.8–98.9)
95.5
(95% CI: 77.2–99.9)
Specificity67.4
(95% CI: 52.0–80.5)
60.9
(95% CI: 45.4–74.9)
Positive predictive value 86.4 (74.5–93.2)92.3 (79.1–96.4)
Negative predictive values70.0 (61.3–78.8)58.7 (49.3–72.8)
ROC curve area0.83 (0.71–0.90), 0.82 (0.71–0.90),

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